From the U.S. healthcare business front, the Justice Department and the other state government appellants have voluntarily dismissed their appeal of an October 2022 district court decision permitting United Healthcare’s acquisition of Change Healthcare to proceed. That acquisition closed within days after that. The appellants had challenged the merger as an antitrust violation.
From the Omicron and siblings front —
U.S. News and World Report tells us
Globally, the number of COVID-19 deaths reported to the World Health Organization in the past four weeks was lower than when the organization first called COVID-19 a pandemic three years ago. The trends are leading experts to be hopeful that the coronavirus pandemic will end in 2023.
“I’m confident that this year we will be able to say that COVID-19 is over as a public health emergency of international concern,” WHO Director-General Tedros Adhanom Ghebreyesus said at a Friday press briefing.
But as attention shifts away from COVID-19, data collecting and sharing is suffering. Many of the trackers people came to rely on during the worst days of the pandemic have shut down, with the CDC announcing last week that it’s “COVID Data Tracker Weekly Review” will end on May 12 – one day after the Biden administration plans to let the COVID-19 emergency declarations expire.
Medscape adds expert U.S. opinions on the endemic status of the disease in the U.S.
Reuters reports
U.S. President Joe Biden on Monday signed a bill that requires declassification of information related to the origins of the coronavirus that causes COVID-19, the White House said.
Biden said he shared Congress’ goal of releasing as much information as possible about the origin of COVID-19.
“In implementing this legislation, my administration will declassify and share as much of that information as possible, consistent with my constitutional authority to protect against the disclosure of information that would harm national security,” Biden said in a statement.
The bill sailed through the Senate and House of Representatives without opposition before being sent to the White House.
From the opioid epidemic front, the Drug Enforcement Administration issued the following public warning about
A sharp increase in the trafficking of fentanyl mixed with xylazine. Xylazine, also known as “Tranq,” is a powerful sedative that the U.S. Food and Drug Administration has approved for veterinary use.
“Xylazine is making the deadliest drug threat our country has ever faced, fentanyl, even deadlier,” said Administrator Milgram. “DEA has seized xylazine and fentanyl mixtures in 48 of 50 States. The DEA Laboratory System is reporting that in 2022 approximately 23% of fentanyl powder and 7% of fentanyl pills seized by the DEA contained xylazine.”
Xylazine and fentanyl drug mixtures place users at a higher risk of suffering a fatal drug poisoning. Because xylazine is not an opioid, naloxone (Narcan) does not reverse its effects. Still, experts always recommend administering naloxone if someone might be suffering a drug poisoning. People who inject drug mixtures containing xylazine also can develop severe wounds, including necrosis—the rotting of human tissue—that may lead to amputation.
According to the CDC, 107,735 Americans died between August 2021 and August 2022 from drug poisonings, with 66 percent of those deaths involving synthetic opioids like fentanyl. The Sinaloa Cartel and Jalisco Cartel in Mexico, using chemicals largely sourced from China, are primarily responsible for the vast majority of the fentanyl that is being trafficked in communities across the United States.
FDA recently communicated to health care providers about the risks to patients exposed to xylazine in illicit drugs. A copy of that communication can be found here: FDA alerts healthcare professionals of risks to patients exposed to xylazine in illicit drugs.
From the obesity treatment front, Reuters reports
Novo Nordisk’s best-selling diabetes treatment drug Ozempic is back on the shelves in the United States after months of shortage, the U.S. Food and Drug Administration (FDA) website showed on Friday.
The main active ingredient in Ozempic is semaglutide, also the key ingredient in Novo’s obesity drug Wegovy, which has been seeing supply shortage due to high demand.
The company said the 0.25 mg, 0.5 mg and the 1 mg doses of Ozempic are available for patients. The 2 mg dose, however, has limited availability until the end of this month, largely due to the demand coupled with overall global supply constraints.
The U.S. Department of Labor has sent its annual report on self-funded group health plans to Congress.